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1

Chemoproteomic profiling of host and pathogen enzymes active in cholera

Hatzios, Stavroula K, Abel, Sören, Martell, Julianne, Hubbard, Troy, Sasabe, Jumpei, Munera, Diana, Clark, Lars, Bachovchin, Daniel A, Qadri, Firdausi, Ryan, Edward T, Davis, Brigid M, Weerapana, Eran

Journal:

Nature Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2016

2

Erratum: Chemoproteomic profiling of host and pathogen enzymes active in cholera

Hatzios, Stavroula K, Abel, Sören, Martell, Julianne, Hubbard, Troy, Sasabe, Jumpei, Munera, Diana, Clark, Lars, Bachovchin, Daniel A, Qadri, Firdausi, Ryan, Edward T, Davis, Brigid M, Weerapana, Eran

Journal:

Nature Chemical Biology

Année:

2016

Fichier:

PDF, 93 KB

2016

3

Unsupervised Learning Approach for Comparing Multiple Transposon Insertion Sequencing Studies

Hubbard, Troy P., D’Gama, Jonathan D., Billings, Gabriel, Davis, Brigid M., Waldor, Matthew K., Imperiale, Michael J.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2019

4

Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements

Hubbard, Troy D., Hsieh, Jui-Hua, Rider, Cynthia V., Sipes, Nisha S., Sedykh, Alexander, Collins, Bradley J., Auerbach, Scott S., Xia, Menghang, Huang, Ruili, Walker, Nigel J., DeVito, Michael J.

Journal:

Applied In Vitro Toxicology

Année:

2019

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2019

5

LIVERPOOL.

Mohiuddin, Maaz S., Abbott, Jordan K., Hubbard, Nicholas, Torgerson, Troy R., Ochs, Hans D., Gelfand, Erwin W.

Journal:

Année:

1909

Langue:

english

Fichier:

PDF, 382 KB

english, 1909

6

Diagnosis and evaluation of primary panhypogammaglobulinemia: A molecular and genetic challenge

Mohiuddin, Maaz S., Abbott, Jordan K., Hubbard, Nicholas, Torgerson, Troy R., Ochs, Hans D., Gelfand, Erwin W.

Journal:

Journal of Allergy and Clinical Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 461 KB

english, 2013

7

[IEEE 2014 IEEE SOI-3D-Subthreshold Microelectronics Technology Unified Conference (S3S) - Millbrae, CA, USA (2014.10.6-2014.10.9)] 2014 SOI-3D-Subthreshold Microelectronics Technology Unified Conference (S3S) - Prototype of multi-stacked memory wafers using low-temperature oxide bonding and ultra-fine-dimension copper through-silicon via interconnects

Lin, Wei, Faltermeier, Johnathan, Winstel, Kevin, Skordas, Spyridon, Graves-Abe, Troy, Batra, Pooja, Herman, Kenneth, Golz, John, Kirihata, Toshiaki, Garant, John, Hubbard, Alex, Cauffman, Kris, Levin

Année:

2014

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2014

8

Genetic analysis of Vibrio parahaemolyticus intestinal colonization

Hubbard, Troy P., Chao, Michael C., Abel, Sören, Blondel, Carlos J., Abel zur Wiesch, Pia, Zhou, Xiaohui, Davis, Brigid M., Waldor, Matthew K.

Journal:

Proceedings of the National Academy of Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1022 KB

english, 2016

9

RpoS and quorum sensing control expression and polar localization of V ibrio cholerae chemotaxis cluster III proteins in vitro and in vivo

Ringgaard, Simon, Hubbard, Troy, Mandlik, Anjali, Davis, Brigid M., Waldor, Matthew K.

Journal:

Molecular Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 13.49 MB

english, 2015

10

CRISPR/Cas9 Screens Reveal Requirements for Host Cell Sulfation and Fucosylation in Bacterial Type III Secretion System-Mediated Cytotoxicity

Blondel, Carlos J., Park, Joseph S., Hubbard, Troy P., Pacheco, Alline R., Kuehl, Carole J., Walsh, Michael J., Davis, Brigid M., Gewurz, Benjamin E., Doench, John G., Waldor, Matthew K.

Journal:

Cell Host & Microbe

Année:

2016

Langue:

english

Fichier:

PDF, 3.43 MB

english, 2016

11

Divergent Ah receptor ligand selectivity during hominin evolution

Hubbard, Troy D., Murray, Iain A., Bisson, William H., Sullivan, Alexis P., Sebastian, Aswathy, Perry, George H., Jablonski, Nina G., Perdew, Gary H.

Journal:

Molecular Biology and Evolution

Année:

2016

Langue:

english

Fichier:

PDF, 3.94 MB

english, 2016

12

A novel AhR ligand, 2AI, protects the retina from environmental stress

Gutierrez, Mark A., Davis, Sonnet S., Rosko, Andrew, Nguyen, Steven M., Mitchell, Kylie P., Mateen, Samiha, Neves, Joana, Garcia, Thelma Y., Mooney, Shaun, Perdew, Gary H., Hubbard, Troy D., Lamba, De

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2016

13

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

Hubbard, Troy D., Murray, Iain A., Bisson, William H., Lahoti, Tejas S., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2015

14

40. Nuclease-Targeted Gene-Editing of FOXP3 in Primary T Cells Creates a Stable and Functional Treg Phenotype

Hubbard, Nicholas W., Hagin, David, Sommer, Karen M., Song, Yumei, Khan, Iram, Scharenberg, Andrew M., Rawlings, David J., Torgerson, Troy R.

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 327 KB

english, 2016

15

316. Successful Editing of the CD40LG Locus in Human Hematopoietic Stem Cells

Curinga, Gabrielle, Leach, Sarah, Singh, Swati, Hubbard, Nick, Hagin, David, Sommer, Karen, Khan, Iram, Song, Yumei, Torgerson, Troy, Scharenberg, Andy, Rawlings, David J.

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 484 KB

english, 2016

16

284. Long-Term Therapeutic Immune Reconstitution in XSCID Canine Model via In Vivo Foamy Virus Delivery of Common Gamma Chain

Chan, Frieda, Humbert, Olivier, Burtner, Christopher, Humphrys, Daniel, Adair, Jennifer, Trobridge, Grant, O'Donnell, Patricia, Hubbard, Nicholas, Torgerson, Troy, Scharenberg, Andrew, Rawlings, David

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 268 KB

english, 2016

17

683. Foamy Virus Gene Therapy Significantly Restores Lymphocyte Development and Function in SCID-X1 Mice

MacQuivey, Matthew, Curinga, Gabrielle, Hubbard, Nick, Khan, Iram, Clough, Courtnee, Humphrys, Daniel, Adair, Jennifer, Trobridge, Grant, Torgerson, Troy, Scharenberg, Andy, Kiem, Hans-Peter, Rawlings

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 299 KB

english, 2016

18

441. Direct Comparison of EF1α and PGK Promoters Reveals Superior Performance of the PGK Promoter for Expression of the Common Gamma Chain in a Canine Model of In Vivo Foamy Virus Gene Therapy for Severe Combined Immunodeficiency

Burtner, Christopher R., Olivier, Humbert, O'Donnell, Patricia, Hubbard, Nicholas, Humphrys, Daniel, Adair, Jennifer E., Trobridge, Grant D., Torgerson, Troy R., Scharenberg, Andrew M., Rawlings, Davi

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 373 KB

english, 2015

19

482. Editing of the CD40L Gene Restores Regulated CD40L Expression in X-HIGM Patient T Cells

Hubbard, Nick, Song, Yumei, Hagin, David, Sommer, Karen, Scharenberg, Andrew, Torgerson, Troy, Rawlings, David

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 315 KB

english, 2015

20

The Nucleoid Binding Protein H-NS Biases Genome-Wide Transposon Insertion Landscapes

Kimura, Satoshi, Hubbard, Troy P., Davis, Brigid M., Waldor, Matthew K.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 423 KB

english, 2016

21

Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner

Hubbard, Troy D., Murray, Iain A., Nichols, Robert G., Cassel, Kaitlyn, Podolsky, Michael, Kuzu, Guray, Tian, Yuan, Smith, Phillip, Kennett, Mary J., Patterson, Andrew D., Perdew, Gary H.

Journal:

Journal of Functional Foods

Année:

2017

Langue:

english

Fichier:

PDF, 3.60 MB

english, 2017

22

Assessment of Ah receptor transcriptional activity mediated by halogenated dibenzo- p -dioxins and dibenzofurans (PXDD/Fs) in human and mouse cell systems

Organtini, Kari L., Hubbard, Troy D., Perdew, Gary H., Dorman, Frank L.

Journal:

Journal of Environmental Science and Health Part A

Année:

2017

Langue:

english

Fichier:

PDF, 829 KB

english, 2017

23

Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses

Muku, Gulsum E, Lahoti, Tejas S, Murray, Iain A, Podolsky, Michael A, Smith, Kayla J, Hubbard, Troy D, Kuzu, Guray, Gowda, Krishne, Amin, Shantu G, Perdew, Gary H

Journal:

Laboratory Investigation

Année:

2017

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2017

24

Time-Resolved Transposon Insertion Sequencing Reveals Genome-Wide Fitness Dynamics during Infection

Yang, Guanhua, Billings, Gabriel, Hubbard, Troy P., Park, Joseph S., Yin Leung, Ka, Liu, Qin, Davis, Brigid M., Zhang, Yuanxing, Wang, Qiyao, Waldor, Matthew K., Rubin, Eric J.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2017

25

Persistent Organic Pollutants Modify Gut Microbiota–Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation

Zhang, Limin, Nichols, Robert G., Correll, Jared, Murray, Iain A., Tanaka, Naoki, Smith, Philip B., Hubbard, Troy D., Sebastian, Aswathy, Albert, Istvan, Hatzakis, Emmanuel, Gonzalez, Frank J., Perdew

Journal:

Environmental Health Perspectives

Année:

2015

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2015

26

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

Warr, Alyson R., Hubbard, Troy P., Munera, Diana, Blondel, Carlos J., Abel zur Wiesch, Pia, Abel, Sören, Wang, Xiaoxue, Davis, Brigid M., Waldor, Matthew K., Sperandio, Vanessa

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 11.01 MB

english, 2019

27

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

Humbert, Olivier, Chan, Frieda, Rajawat, Yogendra S., Torgerson, Troy R., Burtner, Christopher R., Hubbard, Nicholas W., Humphrys, Daniel, Norgaard, Zachary K., OâDonnell, Patricia, Adair, Jennifer

Journal:

Année:

2018

Fichier:

PDF, 1.77 MB

2018

28

Butylparaben multigenerational reproductive assessment by continuous breeding in Hsd:Sprague Dawley SD rats following dietary exposure

Hubbard, Troy D., Brix, Amy, Blystone, Chad R., McIntyre, Barry S., Shockley, Keith, Cunny, Helen, Waidyanatha, Suramya, Turner, Katie J., McBride, Sandra, Roberts, Georgia K.

Journal:

Reproductive Toxicology

Année:

2020

Fichier:

PDF, 3.36 MB

2020

29

Development of an Analytical Method for Quantitation of 2,2Ê¹-Dimorpholinodiethyl Ether (DMDEE) in Rat Plasma, Amniotic Fluid and Fetal Homogenate by UPLCâMS-MS for Determination of Gestational and Lactational Transfer in Rats

Silinski, Melanie A Rehder, Uenoyama, Teruyo, Fernando, Reshan A, Robinson, Veronica G, Roberts, Georgia, Cunny, Helen, Hubbard, Troy, Waidyanatha, Suramya

Journal:

Journal of Analytical Toxicology

Année:

2020

Fichier:

PDF, 582 KB

2020